In , 1 cases of Lymphogranuloma venereum (LGV) were reported in 23 countries. M. Vall-Mayans, I. NoguerBrotes de linfogranuloma venéreo entre hombres homosexuales en Europa, Enferm Infecc Microbiol Clin, 24 (), pp. Request PDF on ResearchGate | Linfogranuloma venéreo: una causa emergente de proctitis en hombres homosexuales en Barcelona | Background and.

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Related links to external sites from Bing. By contrast, in two other patients, one of whom was diagnosed of Linfogdanuloma infection in that episode, the rectal findings were minimal showing mild mucosa erythema and some aphthas, so the infection could be passed unnoticed.

Lymphogranuloma venereum

However, the non-specific histology eliminates the diagnosis of zoster genereo the genital area and minimizes the critical positive values of IgM with respect to VZV infection. A Chlamydia smear from the urethra was also negative. Venefeo patient’s systemic medication included: However, in that case, clinical remission would not have been achieved with antibiotic therapy within weeks, but possibly with therapy directed towards hemodilution or vasodilatation.

From culture to realtime quadriplex polymerase chain reaction.

Such a presentation, in an year-old patient sexually inactive, according to the clinical history is quite unusual. The epidermis showed hyperkeratosis, with both ortho- and parakeratosis. These images are a random sampling from a Bing search on the term “Lymphogranuloma venereum. A microbial smear from lesional tissue was negative for Staphylococus aureus and Clostridium spp, and culture of lesional tissue was negative for Gonococcus Neisseria gonorrhoea.

In the second stage which begins a few weeks or even months after the primary lesion, loco-regional lymphatic chains in the site of inoculation are affected and painful inguinal lymphadenopathy usually appears.

At the acute stage case 1neutrophilic infiltrates prevail; at the subacute stage, histiocytes macrophages linfogranluoma likely predominate case 2whereas at the chronic stage, granulomatous infiltrates probably prevail. The symptoms that led to the request of a rectosigmoidoscopy were anal pain in three of them and anal rectal discharge associated with rectal bleeding in the others. Rectal lymphogranuloma venereum surveillance in France Lymphogranuloma venereum in the United kingdom. Approved by the Advisory Board and accepted for publication on The diagnosis is often made serologically and by exclusion of other causes of inguinal lymphadenopathy or genital ulcers.


Lonfogranuloma severe rectal lesions, endoscopic images can mimic an inflammatory bowel disease 11a rectal carcinoma or a lymphoma.

Sexually Transmitted Disease Chapter. Diagnosis Diagnosis is clinical Aspiration of bubo can be sent to lab but not needed if presentation is classic. Serologies for Infectious Diseases. The endoscopist, due to venerdo large spectrum of possible rectal lesions, should take biopsies routinely for LGV and other sexual transmitted disease and request the laboratory for PCR in tissue of Chlamydia trachomatis serovars L when suspecting this disease.

Uncommon Extragenital Form of Lymphogranuloma venereum: Se presentan cinco casos de LGV con proctitis como signo inicial de linfogranulloma enfermedad.

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How to cite this article. All cases were linfogrxnuloma by polymerase chain reaction technique in rectal tissue. Immunohistochemically, there was evidence of a chronic histiocytic macrophagic and fibrosing balanitis.

All of them were MSM and had multiple sexual partners in the last months. The initial presentation is usually a painless ulcerated papule on the genitalia or distal proctitis. The positive serology with respect to Chlamydia trachomatis and the rapid response to antimicrobial therapy indisputably lead to the interpretation of a rare form of LGV infection. Differential Diagnosis Inflammatory Bowel Disease. The Kappa type paraproteinemia found in this patient could suggest a disorder of the cutaneous microcirculation due to sedimentation of paraproteins combined with thrombocytes, erythrocytes, and fibrinogen in the form of cryoglobulins and cryofibrinogen.


Some authors suggest that the increase of cases reported in recent decades is due to the development of diagnostic tests for serotypes L1, L2 and L3 of Chlamydia sincewhich have emerged these infections previously undiagnosed. Despite HIV infection there was no immune deficiency as in all patients CD4 lymphocytes count was in normal range. Although access to this website is not restricted, the information found here is intended for use by medical providers.

Lymphogranuloma venereum: “a clinical and histopathological chameleon?”

The enlarged lymph nodes in the cervical area could have been mistaken for locoregional metastases patient 1. LGV is a public health problem. Two of the patients had full circumference rectal ulcers and mucopurulent exudate that mimicked anal carcinoma or Crohn’s disease, particularly when those lesions were detected on the digital rectal exploration.

Evidently, LGV is a disease that, within the socalled initial papule or stage 1a, can also be surgically treated. A year-old HIV-negative homosexual man complained of skin problems on his face and enlargement of cervical lymph nodes of three weeks duration Figure 1.

The initial clinical suspicion was of a cutaneous neoplasm Figure 4. Sincemolecular biological venereoo based on high specificity detection of the membrane protein H gene by PCR are used 3. Serology has also been replaced by direct detection tests, but still linfogranulma have some utility in selected cases e. After a detailed analysis of all the bibliographic sources, we cannot entirely exclude the hypothesis that histopathological findings in LGV-patients can also evolve, in concert veneero the clinicopathologic linfogranulloma.

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